https://neurohirurgija.com/neurohirurgija <p>The Official Journal of the Serbian Neurosurgical Society.</p> <p>The Serbian Journal of Neurosurgery is a novel forum in the field of neurosurgery, publishing original peer-reviewed articles of the highest quality, along with relevant comments and correspondences on all neurosurgical and related interdisciplinary topics.</p> <p>Coverage includes all aspects of the case assessment and surgical practice, as well as all types of research, with an emphasis on clinical, rather than experimental material.</p> <p>All papers are submitted to rigorous and independent peer-review, ensuring the journal’s wide citation and its appearance in the major abstracting and indexing services.</p> Serbian Neurosurgical Society en-US Neurohirurgija - The Serbian Journal of Neurosurgery 2955-9162 <p>Authors retain copyright of their work, with first publication rights granted to the publisher.</p> https://neurohirurgija.com/neurohirurgija/article/view/60 <p><strong>Objective:</strong> to present the results of surgical resection of cerebral cavernous malformations (CCMs) in patients with сavernoma-associated epilepsy. To assess the risk factors for an adverse outcome.</p> <p><strong>Methods:</strong> a retrospective analysis of 50 patients with supratentorial CCMs presenting epileptic seizures was performed. All patients underwent surgical CCM resection along with the hemosiderin fringe excision, except in cases when the CCM was localized in eloquent brain regions. In the first 24 hours after the surgery, patients underwent a brain MRI. The MRI study was evaluated by two independent radiologists. The radicality of the CCM and the hemosiderin ring resection around the CCM was evaluated. Long-term results were evaluated using the Engel Surgical Outcome Scale.</p> <p><strong>Results:</strong> The follow-up period was 36.5/33 (21.2; 47.8) months (Max 70.6 months, Min 11.2 months). Forty-four (88%) patients had no recurrence of seizures in the postoperative period. Additionally, 30 (68.2%) of them stopped taking anticonvulsants completely. Four (8%) patients achieved Engel class II outcome (rare seizures remained), and in 2 (4%) of patients, the dynamics in seizure frequency after surgery was not observed. An analysis of the factors influencing the outcome demonstrated that only the radical removal of the hemosiderin ring statistically confirmed its significance in relieving seizures (p=0.043). In patients who didn’t experience seizures during follow-up, the hemosiderin ring was radically removed in 27 (71%) out of 38 cases, and in the group with unsatisfactory results, the hemosiderin ring was radically removed in only 1 (20%) out of 5 patients.</p> <p>Gender, age, seizure types, and anatomical features of the CCM did not affect epilepsy outcomes in the postoperative period.</p> <p><strong>Conclusions</strong>: Surgical CCM resection is an effective method of treating CCM-associated epilepsy with low risks of surgical complications. Total excision of the hemosiderin ring around the CCM is a favorable prognostic factor for the patient's recovery from structural epilepsy when this pathology is present.</p> Dmitry Galaktionov Aleksey Sosnov Konstantin Ovsyannikov Elena Filimonova Olga Subbotina Evgeniya Amelina Galina Moysak Ekaterina Sorokoumova Copyright (c) 2025 Dmitry Galaktionov, Aleksey Sosnov, Konstantin Ovsyannikov, Elena Filimonova, Olga Subbotina, Evgeniya Amelina, Galina Moysak, Ekaterina Sorokoumova https://creativecommons.org/licenses/by/4.0 2025-06-17 2025-06-17 5 1